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Compound category: Benzodiazines
(total 10 related compounds in database)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
N-(furan-2-ylmethylcarbamoyl)-2-(4-oxobenzo[g]quinazolin-3-yl)acetamide Depiction based on curated SMILES O N H O HN O O N N Shigella TTSS (Type III secretion system) Preclinical (in vivo) Case HB, et al. 2020. Biochemistry
[2-[[(1R,2R)-2-methylcyclohexyl]carbamoylamino]-2-oxoethyl] 4-oxo-3-phenylphthalazine-1-carboxylate Depiction based on curated SMILES N N O O N H H H H 3 C O N H O O Shigella TTSS (Type III secretion system) Preclinical (in vivo) Case HB, et al. 2020. Biochemistry
Lapatinib Depiction based on curated SMILES O N NH F Cl S O O N H CH 3 O N Streptococcus Adherence Preclinical (in vivo) Manzer HS, et al. 2022. PLoS Pathog
[6,7-bis(chloranyl)-3-phosphono-quinoxalin-2-yl]phosphonic acid Depiction based on curated SMILES OH OH O P OH OH O P N N Cl Cl Bacillus
Clostridium		 Collagenase
Collagenase		 Preclinical (in vitro)
Preclinical (in vitro)		 Alhayek A, et al. 2022. J Med Chem
[6-(4-chlorophenyl)-3-phosphonoquinoxalin-2-yl]phosphonic acid Depiction based on curated SMILES N Cl OH OH O P OH OH O P N Bacillus
Clostridium		 Collagenase
Collagenase		 Preclinical (in vitro)
Preclinical (in vitro)		 Alhayek A, et al. 2022. J Med Chem
2-(2-Pyridin-3-yl-vinyl)-3-m-tolyl-3H-quinazolin-4-one Depiction based on curated SMILES N O H 3 C N N Klebsiella Aerobactin Preclinical (in vitro) Bailey DC, et al. 2018. SLAS Discov
N-(2,5-dimethylphenyl)-2-(4-oxo-3(4H)-quinazolinyl)acetamide Depiction based on curated SMILES O N N CH 3 O N H CH 3 Mycobacterium Immune modulation Preclinical (in vitro) Karanja CW, et al. 2021. ACS Infect Dis
N-(2-methyl-5-nitrophenyl)-2-(4-oxoquinazolin-3(4H)-yl)acetamide Depiction based on curated SMILES O O N N H 3 C N H _ O O + N Mycobacterium Immune modulation Preclinical (in vitro) Karanja CW, et al. 2021. ACS Infect Dis
N-(5-chloro-2-methylphenyl)-2-(4-oxo-3(4H)-quinazolinyl)acetamide Depiction based on curated SMILES O N N CH 3 O N H Cl Mycobacterium Immune modulation Preclinical (in vitro) Karanja CW, et al. 2021. ACS Infect Dis
2-phenyl-2,3-dihydrophthalazine-1,4-dione Depiction based on curated SMILES O O N HN Shigella VirF Preclinical (in vitro) Hurt JK, et al. 2010. J Biomol Screen
   


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