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4,4-difluoro-1,7-dihydroxy-1,7-diphenylhepta-1,6-diene-3,5-dione

Drug details:
Molecular formula: C19H14F2O4

Classification: Linear diarylheptanoids; Diarylheptanoids; Phenylpropanoids and polyketides; Organic compounds;
Chemical structure:
Depiction based on curated SMILES O O OH F F OH

Evidence for compound's anti-virulence activity:

Yersinia
Related VF: TTSS (Type III secretion system)
Target: Not determined
Drug effect: Blocks translocation of Yop effectors.
Max phase: Preclinical (in vitro)
Publication:
Kauppi AM, et al., 2003. Targeting bacterial virulence: inhibitors of type III secretion in Yersinia. Chem Biol 10(3):241-9.








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