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Compound category: Linear diarylheptanoids
(total 7 related compounds in database)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
3-(3-(4'-Bromo(1,1'-biphenyl)-4-yl)-3-oxo-1-phenylpropyl)-4-hydroxy-2-benzopyrone Depiction based on curated SMILES O O Br O HO Brucella VirB type IV secretion system Preclinical (in vivo) Paschos A, et al. 2011. Infect Immun
Alnustone Depiction based on curated SMILES O Streptococcus Pneumolysin Preclinical (in vivo) Zhang C, et al. 2022. Fitoterapia
Curcumin Depiction based on curated SMILES OH HO H 3 C O H 3 C O O O Acinetobacter
Bacillus
Clostridium
Enterococcus
Pseudomonas
BfmRS
Biofilm
Collagenase
Biofilm
Quorum sensing
Preclinical (in vitro)
Preclinical (in vitro)
Preclinical (in vitro)
Preclinical (in vitro)
Preclinical (in vitro)
Raorane CJ, et al. 2019. Front Microbiol
Fernandes S, et al. 2023. Food Res Int
Nitulescu G, et al. 2022. Life (Basel)
Oda DF, et al. 2019. Int Endod J
[2,4-Dihydroxy-3-(3-methyl-2-buten-1-yl)phenyl][(1R,2S,6S)-6-(2,4-dihydroxyphenyl)-2-[4-[(1E)-2-(2,4-dihydroxyphenyl)ethenyl]-2,6-dihydroxyphenyl]-4-methyl-3-cyclohexen-1-yl]methanone Depiction based on curated SMILES HO H 3 C CH 3 OH HO OH OH OH H H H CH 3 HO OH O Mycobacterium Exoenzyme Preclinical (in vitro) Mascarello A, et al. 2013. PLoS One
Rottlerin Depiction based on curated SMILES O CH 3 H 3 C OH OH CH 3 OH HO O HO H 3 C O Pseudomonas Biofilm Preclinical (in vitro) Sambanthamoorthy K, et al. 2014. Biofouling
4,4-difluoro-1,7-dihydroxy-1,7-diphenylhepta-1,6-diene-3,5-dione Depiction based on curated SMILES O O OH F F OH Yersinia TTSS (Type III secretion system) Preclinical (in vitro) Kauppi AM, et al. 2003. Chem Biol
4-[(E)-2-[5-[(E)-2-[4-(dimethylamino)phenyl]ethenyl]-2-methyltetrazolo[1,5-a]pyrimidin-8-ium-7-yl]ethenyl]-N,N-dimethylaniline Depiction based on curated SMILES CH 3 CH 3 N CH 3 H 3 C N H 3 C N + N N N N Yersinia TTSS secreted effectors Preclinical (in vitro) Hu X, et al. 2013. Bioorg Med Chem Lett
   
   
   
   
   
   
   


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