Drug details:
Molecular formula: C₁₈H₈BrF₃N₂O₂S₂

Standard name: 5-bromo-3-[4-hydroxy-2-sulfanylidene-3-[3-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]indol-2-one

Synonym:

5-bromo-3-{4-oxo-2-thioxo-3-[3-(trifluoromethyl)phenyl]-1,3-thiazolidin-5-ylidene}-1,3-dihydro-2H-indol-2-one

Curated SMILES: O=C1NC2=C(C=C(Br)C=C2)/C1=C1/SC(=S)N(C2=CC(C(F)(F)F)=CC=C2)C1=O

Evidence for compound's anti-virulence activity:

Yersinia
Related VF: TTSS secreted effectors
Target: YopH
Drug effect: Targets the phosphotyrosine-binding pocket of YopH.
Max phase: Preclinical (in vitro)
Publication:
Hu X, et al., 2013. Inhibitors of the Yersinia protein tyrosine phosphatase through high throughput and virtual screening approaches. Bioorg Med Chem Lett 23(4):1056-62.