Drug details:
Molecular formula: C₂₀H₁₄N₂O₈

Standard name: 3-[13-(2-carboxyethyl)-5,7,12,14-tetraoxo-6,13-diazatetracyclo[6.6.2.04,16.011,15]hexadeca-1(15),2,4(16),8,10-pentaen-6-yl]propanoic acid

Synonyms:

3,3'-(1,3,6,8-tetraoxo-1,3,6,8-tetrahydrobenzo[lmn][3,8]phenanthroline-2,7-diyl)dipropanoic acid 3-[7-(3-hydroxy-3-oxopropyl)-1,3,6,8-tetraoxo-1,3,6,8-tetrahydrobenzo[lmn][3,8]phenanthrolin-2-yl]propanoic acid

Curated SMILES: O=C(O)CCN1C(=O)C2=CC=C3C(=O)N(CCC(=O)O)C(=O)C4=C3C2=C(C=C4)C1=O

Evidence for compound's anti-virulence activity:

Yersinia
Related VF: TTSS secreted effectors
Target: YopH
Drug effect: Targets the phosphotyrosine-binding pocket of YopH.
Max phase: Preclinical (in vitro)
Publication:
Eriksson J, et al., 2012. Small molecule screening for inhibitors of the YopH phosphatase of Yersinia pseudotuberculosis. Adv Exp Med Biol 954:357-63.