Drug details:
Molecular formula: C₈H₇NO₅

Standard name: 2-(4-hydroxy-3-nitrophenyl)acetic acid

Synonyms:

2-(4-HYDROXY-3-NITROPHENYL)ACETIC ACID (4-hydroxy-3-nitrophenyl)acetic acid Benzeneacetic acid, 4-hydroxy-3-nitro- 3-nitro-4-hydroxyphenylacetic acid 3-Nitro-4-hydroxy phenylacetic acid 4-Hydroxy-3-nitrophenylacetic Acid-d5 4-hydroxy-5-nitrophenyl acetic acid 4-Hydroxy-3-nitrophenylacetate 3-nitro 4-hydroxyphenyl acetic acid ......

Curated SMILES: O=C(O)CC1=CC([N+](=O)[O-])=C(O)C=C1

Evidence for compound's anti-virulence activity:

Yersinia
Related VF: TTSS secreted effectors
Target: YopH
Drug effect: Targets the phosphotyrosine-binding pocket of YopH.
Max phase: Preclinical (in vivo)
Publication:
Liang F, et al., 2003. Aurintricarboxylic acid blocks in vitro and in vivo activity of YopH, an essential virulent factor of Yersinia pestis, the agent of plague. J Biol Chem 278(43):41734-41.