Drug details:
Molecular formula: C₁₄H₈O₃

Standard name: 9-oxofluorene-1-carboxylic acid

Synonyms:

9-oxofluorene-1-carboxylic acid 9-oxo-9H-fluorene-1-carboxylic acid 9-Oxo-9H-fluorenecarboxylic acid 9H-Fluorene-1-carboxylic acid, 9-oxo- EINECS 216-396-5 9-Oxo-9H-fluorene-1-carboxylicacid 9H-Fluorenecarboxylic acid, 9-oxo- 9-Fluorenone-1-carboxylic acid, 99%

Curated SMILES: C1=CC=C2C(=C1)C3=C(C2=O)C(=CC=C3)C(=O)O

Evidence for compound's anti-virulence activity:

Yersinia
Related VF: TTSS secreted effectors
Target: YopH
Drug effect: Targets the phosphotyrosine-binding pocket of YopH.
Max phase: Preclinical (in vivo)
Publication:
Liang F, et al., 2003. Aurintricarboxylic acid blocks in vitro and in vivo activity of YopH, an essential virulent factor of Yersinia pestis, the agent of plague. J Biol Chem 278(43):41734-41.