Drug details:
Molecular formula: C₈H₄F₄O₂

Standard name: 2-fluoro-6-(trifluoromethyl)benzoic acid

Synonyms:

Benzoic acid, 2-fluoro-6-(trifluoromethyl)- 2-fluoro-6-trifluoromethylbenzoic acid 6-fluoro-2-trifluoromethylbenzoic acid alpha,alpha,alpha,6-Tetrafluoro-o-toluic Acid 2-Fluoro-6-(trifluoromethyl)benzoicacid 2-fluoro-6-trifluoromethyl-benzoic acid 2-Fluoro-6-(trifluoromethyl)benzoic acid, 99%

Curated SMILES: C1=CC(=C(C(=C1)F)C(=O)O)C(F)(F)F

Evidence for compound's anti-virulence activity:

Yersinia
Related VF: TTSS secreted effectors
Target: YopH
Drug effect: Targets the phosphotyrosine-binding pocket of YopH.
Max phase: Preclinical (in vivo)
Publication:
Liang F, et al., 2003. Aurintricarboxylic acid blocks in vitro and in vivo activity of YopH, an essential virulent factor of Yersinia pestis, the agent of plague. J Biol Chem 278(43):41734-41.