Drug details:
Molecular formula: C₁₁H₇FO₂

Standard name: 4-fluoronaphthalene-1-carboxylic acid

Synonyms:

4-fluoronaphthalene-1-carboxylic acid 1-Naphthalenecarboxylic acid, 4-fluoro- 4-fluoro-1-naphthalenecarboxylic acid EINECS 209-346-9 4-fluoronaphthalenecarboxylic acid 4-Fluoro-1-naphthoic acid, 96% 1-NAPHTHOIC ACID, 4-FLUORO- 4-fluoro-1-naphthalene carboxylic acid 4-fluoro-naphthalene-1-carboxylic acid

Curated SMILES: C1=CC=C2C(=C1)C(=CC=C2F)C(=O)O

Evidence for compound's anti-virulence activity:

Yersinia
Related VF: TTSS secreted effectors
Target: YopH
Drug effect: Targets the phosphotyrosine-binding pocket of YopH.
Max phase: Preclinical (in vivo)
Publication:
Liang F, et al., 2003. Aurintricarboxylic acid blocks in vitro and in vivo activity of YopH, an essential virulent factor of Yersinia pestis, the agent of plague. J Biol Chem 278(43):41734-41.