Drug details:
Molecular formula: C₁₁H₈O₄

Standard name: 3,5-dihydroxynaphthalene-2-carboxylic acid

Synonyms:

3,5-dihydroxynaphthalene-2-carboxylic acid 2,8-Dihydroxy-3-naphthoic acid 2-Naphthoic acid, 3,5-dihydroxy- 2-Naphthalenecarboxylic acid, 3,5-dihydroxy- 3,5-Dihydroxy-2-naphthalenecarboxylic Acid 1,7-Dihydroxy-6-naphthoic acid 3,5-Dihydroxy-2-carboxynaphthalene EINECS 201-900-8 1,7-Dihydroxy-6-naphthalenecarboxylic acid ......

Curated SMILES: C1=CC2=CC(=C(C=C2C(=C1)O)O)C(=O)O

Evidence for compound's anti-virulence activity:

Yersinia
Related VF: TTSS secreted effectors
Target: YopH
Drug effect: Targets the phosphotyrosine-binding pocket of YopH.
Max phase: Preclinical (in vivo)
Publication:
Liang F, et al., 2003. Aurintricarboxylic acid blocks in vitro and in vivo activity of YopH, an essential virulent factor of Yersinia pestis, the agent of plague. J Biol Chem 278(43):41734-41.