Drug details:
Molecular formula: C₃₃H₂₃Cl₃N₂O₄

Standard name: 5-[4-[[4-(3-carboxy-4-chloroanilino)phenyl]-chloro-phenylmethyl]anilino]-2-chlorobenzoic acid

Synonyms:

5-[4-[[4-(3-carboxy-4-chloroanilino)phenyl]-chloro-phenylmethyl]anilino]-2-chlorobenzoic acid 4,4'-BIS(3-CARBOXY-4-CHLOROPHENYL-AMINO)TRITYL CHLORIDE triphenylmethane derivative, 4 5,5'-(4,4'-(chloro(phenyl)methylene)bis(4,1-phenylene)bis(azanediyl))bis(2-chlorobenzoic acid) 5-[4-[[4-(3-carboxy-4-chloro-anilino)phenyl]-chloro-phenyl-methyl]anilino]-2-chloro-benzoic acid

Curated SMILES: O=C(O)C1=C(Cl)C=CC(NC2=CC=C(C(Cl)(C3=CC=CC=C3)C3=CC=C(NC4=CC(C(=O)O)=C(Cl)C=C4)C=C3)C=C2)=C1

Evidence for compound's anti-virulence activity:

Yersinia
Related VF: TTSS secreted effectors
Target: YopH
Drug effect: Targets the phosphotyrosine-binding pocket of YopH.
Max phase: Preclinical (in vivo)
Publication:
Liang F, et al., 2003. Aurintricarboxylic acid blocks in vitro and in vivo activity of YopH, an essential virulent factor of Yersinia pestis, the agent of plague. J Biol Chem 278(43):41734-41.