Drug details:
Molecular formula: C₇H₅IO₂

Standard name: 4-iodobenzoic acid

Synonyms:

p-Iodobenzoic acid Benzoic acid, 4-iodo- Benzoic acid, p-iodo- p-Iodobenzenecarboxylic acid 4-Iodo-benzoic acid 4-Jodbenzoesaeure 4-Jodbenzoesaeure [German] EINECS 210-603-2 4-Iodobenzoicacid ......

Curated SMILES: C1=CC(=CC=C1C(=O)O)I

Evidence for compound's anti-virulence activity:

Yersinia
Related VF: TTSS secreted effectors
Target: YopH
Drug effect: Targets the phosphotyrosine-binding pocket of YopH.
Max phase: Preclinical (in vivo)
Publication:
Liang F, et al., 2003. Aurintricarboxylic acid blocks in vitro and in vivo activity of YopH, an essential virulent factor of Yersinia pestis, the agent of plague. J Biol Chem 278(43):41734-41.