Drug details:
Molecular formula: C₂₁H₁₅Cl₃O₂

Standard name: 3,3,3-tris(4-chlorophenyl)propanoic acid

Synonyms:

3,3,3-Tris(4-chlorophenyl)propanoic acid 3,3,3-Tris(p-chlorophenyl)propionic acid 3,3,3-tris-(4-Chlorophenyl)propionic acid Benzenepropanoic acid, 4-chloro-.beta.,.beta.-bis(4-chlorophenyl)- C21H15Cl3O2 3,3,3-TRIS(4-CHLOROPHENYL)PROPIONIS ACID EINECS 218-509-3 3,3,3-Tris(4-chlorophenyl)propionicacid 3,3,3,-Tris(4-Chlorophenyl)propionic acid ......

Curated SMILES: O=C(O)CC(C1=CC=C(Cl)C=C1)(C1=CC=C(Cl)C=C1)C1C=CC(Cl)=CC1

Evidence for compound's anti-virulence activity:

Yersinia
Related VF: TTSS secreted effectors
Target: YopH
Drug effect: Targets the phosphotyrosine-binding pocket of YopH.
Max phase: Preclinical (in vitro)
Publication:
Liang F, et al., 2003. Aurintricarboxylic acid blocks in vitro and in vivo activity of YopH, an essential virulent factor of Yersinia pestis, the agent of plague. J Biol Chem 278(43):41734-41.