Drug details:
Molecular formula: C₁₅H₉NO₆S

Standard name: 5-[5-[(Z)-(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]furan-2-yl]-2-hydroxybenzoic acid

Synonyms:

5-[5-[(Z)-(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]furan-2-yl]-2-hydroxybenzoic acid 5-(5-{[(5Z)-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl}furan-2-yl)-2-hydroxybenzoic acid 5-[5-(2,4-Dioxothiazolidine-5-ylidenemethyl)-2-furanyl]-2-hydroxybenzoic acid

Curated SMILES: O=C1NC(=O)/C(=C/C2=CC=C(C3=CC(C(=O)O)=C(O)C=C3)O2)S1

Evidence for compound's anti-virulence activity:

Yersinia
Related VF: TTSS secreted effectors
Target: YopH
Drug effect: Targets the phosphotyrosine-binding pocket of YopH.
Max phase: Preclinical (in vitro)
Publication:
Tautz L, et al., 2005. Inhibition of Yersinia tyrosine phosphatase by furanyl salicylate compounds. J Biol Chem 280(10):9400-8.