Drug details:
Molecular formula: C₂₃H₁₈N₄O₅

Standard name: (E)-N-[4-(1-hydroxy-6-nitrobenzimidazol-2-yl)phenyl]-3-(4-methoxyphenyl)prop-2-enamide

Curated SMILES: COC1=CC=C(C=C1)/C=C/C(=O)NC2=CC=C(C=C2)C3=NC4=C(N3O)C=C(C=C4)[N+](=O)[O-]

Evidence for compound's anti-virulence activity:

Yersinia
Related VF: TTSS (Type III secretion system)
Target: VirF/LcrF
Drug effect: Targets the conserved DNA-binding domain of LcrF.
Max phase: Preclinical (in vitro)
Publication:
Kim OK, et al., 2009. N-hydroxybenzimidazole inhibitors of the transcription factor LcrF in Yersinia: novel antivirulence agents. J Med Chem 52(18):5626-34.