Drug details:
Molecular formula: C₂₃H₁₇FN₄O₄

Standard name: (E)-3-(4-fluorophenyl)-N-[4-(1-hydroxy-5-methyl-6-nitrobenzimidazol-2-yl)phenyl]prop-2-enamide

Curated SMILES: [H]N(C(=O)/C=C/C1=CC=C(F)C=C1)C1=CC=C(C2=NC3=CC(C)=C([N+](=O)[O-])C=C3N2O)C=C1

Evidence for compound's anti-virulence activity:

Yersinia
Related VF: TTSS (Type III secretion system)
Target: VirF/LcrF
Drug effect: Targets the conserved DNA-binding domain of LcrF.
Max phase: Preclinical (in vitro)
Publication:
Kim OK, et al., 2009. N-hydroxybenzimidazole inhibitors of the transcription factor LcrF in Yersinia: novel antivirulence agents. J Med Chem 52(18):5626-34.