Drug details:
Molecular formula: C₂₇H₂₄N₄O₅S

Standard name: 2-hydroxy-5-[5-[(E)-3-oxo-3-[4-(3-phenyl-1,2,4-thiadiazol-5-yl)-1,4-diazepan-1-yl]prop-1-enyl]furan-2-yl]benzoic acid

Curated SMILES: C1CN(CCN(C1)C(=O)/C=C/C2=CC=C(O2)C3=CC(=C(C=C3)O)C(=O)O)C4=NC(=NS4)C5=CC=CC=C5

Evidence for compound's anti-virulence activity:

Yersinia
Related VF: TTSS secreted effectors
Target: YopH
Drug effect: Targets the phosphotyrosine-binding pocket of YopH.
Max phase: Preclinical (in vitro)
Publication:
Leone M, et al., 2010. NMR-based design and evaluation of novel bidentate inhibitors of the protein tyrosine phosphatase YopH. Chem Biol Drug Des 76(1):10-6.