Drug details:
Molecular formula: C₁₃H₁₁BrN₂O

Standard name: 4-bromo-2-(pyridin-3-ylmethyliminomethyl)phenol

Curated SMILES: OC1=CC=C(Br)C=C1/C=N/CC1=CC=CN=C1

Evidence for compound's anti-virulence activity:

Escherichia
Related VF: TTSS (Type III secretion system)
Target: Not determined
Drug effect: Having a significant and dramatic effect on the expression of Ler-dependent genes that encode virulence factors within (EspB, Tir, type III apparatus) and outside (EspC) the LEE.
Max phase: Preclinical (in vitro)
Publication:
Gauthier A, et al., 2005. Transcriptional inhibitor of virulence factors in enteropathogenic Escherichia coli. Antimicrob Agents Chemother 49(10):4101-9.