Drug details:
Molecular formula: C₂₂H₂₇NO₇

Standard name: 3-[4-[(R)-hydroxy-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]methyl]-3-methylphenyl]-N-methylbenzamide

Curated SMILES: CNC(=O)C1=CC(C2=CC=C([C@@H](O)C3OC(CO)C(O)C(O)C3O)C(C)=C2)=CC=C1

Evidence for compound's anti-virulence activity:

Escherichia
Related VF: Type 1 fimbriae
Target: FimH
Drug effect: Bound to the FimH lectin domain to interfere with bacterial adhesion, invasion and biofilm formation.
Max phase: Preclinical (in vivo)
Publication:
Mydock-McGrane L, et al., 2016. Antivirulence C-Mannosides as Antibiotic-Sparing, Oral Therapeutics for Urinary Tract Infections. J Med Chem 59(20):9390-9408.