Drug details:
Molecular formula: C₂₂H₂₇NO₆

Standard name: N-methyl-3-[3-methyl-4-[[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]methyl]phenyl]benzamide

Curated SMILES: CC1=C(C=CC(=C1)C2=CC(=CC=C2)C(=O)NC)C[C@@H]3[C@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O

Evidence for compound's anti-virulence activity:

Escherichia
Related VF: Type 1 fimbriae
Target: FimH
Drug effect: Bound to the FimH lectin domain to interfere with bacterial adhesion, invasion and biofilm formation.
Max phase: Preclinical (in vivo)
Publication:
Mydock-McGrane L, et al., 2016. Antivirulence C-Mannosides as Antibiotic-Sparing, Oral Therapeutics for Urinary Tract Infections. J Med Chem 59(20):9390-9408.