Drug details:
Molecular formula: C₁₀H₁₂O₂

Standard name: 2-methoxy-4-prop-2-enylphenol

Synonyms:

4-Allyl-2-methoxyphenol 4-Allylguaiacol Eugenic acid Allylguaiacol p-Eugenol Caryophyllic acid p-Allylguaiacol 2-Methoxy-4-prop-2-enylphenol 2-Methoxy-4-allylphenol ......

Curated SMILES: COC1=C(C=CC(=C1)CC=C)O

Evidence for compound's anti-virulence activity:

Campylobacter
Related VFcategory: Regulation
Target: Not determined
Drug effect: Downregulats critical virulence genes including genes coding for attachment, motility and invasion.
Max phase: Preclinical (in vitro)
Publication:
Ammar AM, et al., 2020. Prevalence, Antimicrobial Susceptibility, Virulence and Genotyping of Campylobacter jejuni with a Special Reference to the Anti-Virulence Potential of Eugenol and Beta-Resorcylic Acid on Some Multi-Drug Resistant Isolates in Egypt. Animals (Basel) 11(1):3.

Enterococcus
Related VFcategory: Biofilm
Target: Not determined
Drug effect: Biofilm eradication.
Max phase: Preclinical (in vitro)
Publication:
Miladi H, et al., 2017. Synergistic effect of eugenol, carvacrol, thymol, p-cymene and gamma-terpinene on inhibition of drug resistance and biofilm formation of oral bacteria. Microb Pathog 112:156-163.