Drug details:
Molecular formula: C₂₁H₃₈ClN

Standard name: 1-hexadecylpyridin-1-ium;chloride

Synonyms:

1-hexadecylpyridin-1-ium chloride hexadecylpyridinium chloride 1-Hexadecylpyridinium chloride Ceprim Pristacin Aktivex Cepacol 1-Cetylpyridinium chloride Biosept ......

Curated SMILES: CCCCCCCCCCCCCCCC[N+]1=CC=CC=C1.[Cl-]

Evidence for compound's anti-virulence activity:

Helicobacter
Related VF: BabA (Blood group antigen binding adhesin); Flagella; Urease
Target: Not determined
Drug effect: Reduces virulence and adherence factors expression,including flaA, flaB, babB, alpA, alpB, ureE, and ureF,and inhibits urease activity.
Max phase: Preclinical (in vitro)
Publication:
Xun M, et al., 2024. In vitro anti-Helicobacter pylori activity and antivirulence activity of cetylpyridinium chloride. PLoS One 19(4):e0300696.