Drug details:
Molecular formula: C₈H₁₁O₅P

Standard name: 2-(3,4-dihydroxyphenyl)ethylphosphonic acid

Synonyms:

3,4-Dihydroxyphenethylphosphonic Acid 2-(3,4-dihydroxyphenyl)ethylphosphonic acid

Curated SMILES: C1=CC(=C(C=C1CCP(=O)(O)O)O)O

Evidence for compound's anti-virulence activity:

Helicobacter
Related VF: Urease
Target: Urease
Drug effect: Exhibits significant anti-urease potential.
Max phase: Preclinical (in vitro)
Publication:
Maslanka M, et al., 2023. Inhibitory activity of catecholic phosphonic and phosphinic acids against Helicobacter pylori ureolysis. Eur J Med Chem 257:115528.