Drug details:
Molecular formula: C₂₁H₂₄F₃N₃S

Standard name: 10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine

Synonyms:

Trifluperazine Trifluoroperazine Trifluoperazin Flurazine Triflurin Triperazine Trifluoperazina Trifluoromethylperazine Trifluoperazinum ......

Curated SMILES: CN1CCN(CC1)CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)C(F)(F)F

Evidence for compound's anti-virulence activity:

Neisseria
Related VF: Type IV pili
Target: Not determined
Drug effect: Blocks functions associated with Type IV pili by affecting piliation within minutes.
Max phase: Preclinical (in vivo)
Publication:
Denis K, et al., 2019. Targeting Type IV pili as an antivirulence strategy against invasive meningococcal disease. Nat Microbiol 4(6):972-984.