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Compound category: Phenothiazines
(total 3 related compounds in database)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
Thioridazine Depiction based on curated SMILES CH 3 S S H 3 C N N Neisseria Type IV pili Preclinical (in vivo) Denis K, et al. 2019. Nat Microbiol
Trifluoperazine Depiction based on curated SMILES F F F S CH 3 N N N Neisseria Type IV pili Preclinical (in vivo) Denis K, et al. 2019. Nat Microbiol
Perphenazine Depiction based on curated SMILES HO Cl S N N N Coxiella
Legionella
Dot/Icm T4SS
Dot/Icm (Defect in organella trafficking/intracellular multiplication)
Preclinical (in vitro)
Preclinical (in vitro)
Cheng E, et al. 2022. mBio
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   


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