Drug details:
Molecular formula: C₂₃H₂₁NO₃S

Standard name: (3R)-8-cyclopropyl-7-[(4-methylnaphthalen-1-yl)methyl]-5-oxo-2,3-dihydro-[1,3]thiazolo[3,2-a]pyridine-3-carboxylic acid

Synonym:

(3R)-8-cyclopropyl-7-[(4-methyl-1-naphthyl)methyl]-5-oxo-2,3-dihydrothiazolo[3,2-a]pyridine-3-carboxylic acid

Curated SMILES: C1(C(C2)C2)=C(S2)N([C@@H](C2)C(O)=O)C(C=C1CC(C=C1)=C(C=CC2)C(C=2)=C1C)=O

Evidence for compound's anti-virulence activity:

Listeria
Related VF: PrfA (Pleiotropic regulatory factor)
Target: PrfA
Drug effect: Binds to PrfA, the master virulence regulator to decrease virulence factor expression.
Max phase: Preclinical (in vitro)
Publication:
Kulén M, et al., 2018. Structure-Based Design of Inhibitors Targeting PrfA, the Master Virulence Regulator of Listeria monocytogenes. J Med Chem 61(9):4165-4175.