Drug details:
Molecular formula: C₁₈H₁₇ClN₄O

Standard name: (E)-N-[4-(2-amino-1H-imidazol-5-yl)phenyl]-3-phenylprop-2-enamide;hydrochloride

Curated SMILES: C1=CC=C(C=C1)/C=C/C(=O)NC2=CC=C(C=C2)C3=CN=C(N3)N.Cl

Evidence for compound's anti-virulence activity:

Escherichia
Related VFcategory: Biofilm
Target: Not determined
Drug effect: Inhibits biofilm formation.
Max phase: Preclinical (in vitro)
Publication:
Bunders CA, et al., 2010. Identification of aryl 2-aminoimidazoles as biofilm inhibitors in Gram-negative bacteria. Bioorg Med Chem Lett 20(12):3797-800.