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Compound category: Cinnamic acids and derivatives
(total 6 related compounds in database)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
3-Nitrocinnamic acid Depiction based on curated SMILES + N O _ O O HO Yersinia TTSS secreted effectors Preclinical (in vivo) Liang F, et al. 2003. J Biol Chem
Rosmarinic acid Depiction based on curated SMILES HO HO OH OH O O OH O H Aeromonas Biofilm Preclinical (in vivo) Rama Devi K, et al. 2016. Biofouling
(E)-N-[4-(2-amino-1H-imidazol-5-yl)phenyl]-3-phenylprop-2-enamide;hydrochloride Depiction based on curated SMILES ClH H 2 N N H N N H O Escherichia Biofilm Preclinical (in vitro) Bunders CA, et al. 2010. Bioorg Med Chem Lett
1-(2,5-dimethoxyphenyl)-3-(naphthalen-1-yl)prop-2-en-1-one Depiction based on curated SMILES CH 3 O CH 3 O O Mycobacterium Exoenzyme Preclinical (in vitro) Chiaradia LD, et al. 2008. Bioorg Med Chem Lett; Mascarello A, et al. 2010. Bioorg Med Chem
1-(2,5-dimethoxyphenyl)-3-(naphthalen-2-yl)prop-2-en-1-one Depiction based on curated SMILES H 3 C O H 3 C O O Mycobacterium Exoenzyme Preclinical (in vitro) Chiaradia LD, et al. 2008. Bioorg Med Chem Lett; Mascarello A, et al. 2010. Bioorg Med Chem
(E)-N-(6-methylsulfonyl-1,3-benzothiazol-2-yl)-3-[3-[(2-methyl-1,3-thiazol-4-yl)methoxy]phenyl]prop-2-enamide Depiction based on curated SMILES S S O O CH 3 S H 3 C N HN O O N Shigella TTSS (Type III secretion system) Preclinical (in vitro) Case HB, et al. 2018. Biochemistry
   
   
   
   
   
   
   
   
   


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