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Rosmarinic acid

Drug details:
Molecular formula: C18H16O8

Classification: Hydroxycinnamic acids and derivatives; Cinnamic acids and derivatives; Phenylpropanoids and polyketides; Organic compounds;
Synonyms:  Rosemary acid
Labiatenic acid
Rosmarinicacid
Labiatic acid
(R)-rosmarinic acid
trans-Rosmarinic acid
Rosemaric acid
Rosmarinate
Rosmarinic acid racemate
......

Chemical structure:
Depiction based on curated SMILES HO HO OH OH O O OH O H

Evidence for compound's anti-virulence activity:

Aeromonas
Related VFcategory: Biofilm
Target: Not determined
Drug effect: Inhibits quorum sensing mediated biofilm formation and reduces virulence factor production.
Max phase: Preclinical (in vivo)
Publication:
Rama Devi K, et al., 2016. In vitro and in vivo efficacy of rosmarinic acid on quorum sensing mediated biofilm formation and virulence factor production in Aeromonas hydrophila. Biofouling 32(10):1171-1183.








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