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UM0125848 (it's an internal name reported in related literature)

Drug details:
Classification: Benzoic acids and derivatives; Benzene and substituted derivatives; Benzenoids; Organic compounds;

Chemical structure:
Depiction based on curated SMILES _ O OH OH O O O + N N N H

Evidence for compound's anti-virulence activity:

Brucella
Related VF: VirB type IV secretion system
Target: VirB8
Drug effect: Inhibits T4SS by targeting an essential assembly protein VirB8.
Max phase: Preclinical (in vivo)
Publication:
Smith MA, et al., 2012. Identification of the binding site of Brucella VirB8 interaction inhibitors. Chem Biol 19(8):1041-8.








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