Drug details:
Molecular formula: C₁₆H₁₃FN₄S

Standard name: N-(2-fluorophenyl)-4-methyl-3-(pyridin-4-ylmethylideneamino)-1,3-thiazol-2-imine

Curated SMILES: CC1=CSC(=NC2=CC=CC=C2F)N1N=CC3=CC=NC=C3

Evidence for compound's anti-virulence activity:

Burkholderia
Related VF: Quorum-sensing
Target: BmaI1
Drug effect: Inhibits acyl-HSL synthase BmaI1 activity.
Max phase: Preclinical (in vitro)
Publication:
Christensen QH, et al., 2013. A high-throughput screen for quorum-sensing inhibitors that target acyl-homoserine lactone synthases. Proc Natl Acad Sci U S A 110(34):13815-20.