Drug details:
Molecular formula: C₁₁H₉BrN₄

Standard name: 5-(6-bromo-1H-indol-3-yl)-1H-imidazol-2-amine

Curated SMILES: C1=CC2=C(C=C1Br)NC=C2C3=CN=C(N3)N

Evidence for compound's anti-virulence activity:

Mycobacterium
Related VFcategory: Biofilm
Target: Not determined
Drug effect: Inhibits and disperses biofilms.
Max phase: Preclinical (in vitro)
Publication:
Brackett SM, et al., 2020. Meridianin D analogues possess antibiofilm activity against Mycobacterium smegmatis. RSC Med Chem 11(1):92-97.

Staphylococcus
Related VFcategory: Biofilm
Target: Not determined
Drug effect: Inhibits biofilm formation and increases the potency of colistin.
Max phase: Preclinical (in vitro)
Publication:
Huggins WM, et al., 2018. Meridianin D Analogues Display Antibiofilm Activity against MRSA and Increase Colistin Efficacy in Gram-Negative Bacteria. ACS Med Chem Lett 9(7):702-707.