Drug details:
Molecular formula: C₁₅H₁₈Cl₂N₄O

Standard name: 5-tert-butyl-2-[(2,4-dichlorophenyl)methyl]pyrazole-3-carbohydrazide

Synonyms:

5-tert-butyl-2-[(2,4-dichlorophenyl)methyl]pyrazole-3-carbohydrazide 1H-Pyrazole-5-carboxylic acid, 1-[(2,4-dichlorophenyl)methyl]-3-(1,1-dimethylethyl)-, hydrazide 3-tert-Butyl-1-[(2,4-dichlorophenyl)methyl]-1H-pyrazole-5-carbohydrazide

Curated SMILES: CC(C)(C)C1=NN(CC2=C(Cl)C=C(Cl)C=C2)C(C(=O)NN)=C1

Evidence for compound's anti-virulence activity:

Mycobacterium
Related VFcategory: Motility
Target: Not determined
Drug effect: Inhibits sliding motility and then results in a decrease in bacterial virulence.
Max phase: Preclinical (in vitro)
Publication:
Ouertatani-Sakouhi H, et al., 2017. Inhibitors of Mycobacterium marinum virulence identified in a Dictyostelium discoideum host model. PLoS One 12(7):e0181121.