Drug details:
Molecular formula: C₁₉H₁₆ClNO₄S

Standard name: 9-(4-chlorobenzoyl)-5,6,7,8-tetrahydrocarbazole-3-sulfonic acid

Curated SMILES: C1CCC2=C(C1)C3=C(N2C(=O)C4=CC=C(C=C4)Cl)C=CC(=C3)S(=O)(=O)O

Evidence for compound's anti-virulence activity:

Mycobacterium
Related VFcategory: Exoenzyme
Target: PtpB
Drug effect: Inhibits protein tyrosine phosphatase B (PtpB) to interfere with signal transduction pathways in macrophages.
Max phase: Preclinical (in vitro)
Publication:
Nören-Müller A, et al., 2006. Discovery of protein phosphatase inhibitor classes by biology-oriented synthesis. Proc Natl Acad Sci U S A 103(28):10606-11.