Drug details:
Molecular formula: C₃₁H₂₄N₂O₅S

Standard name: 2-benzoyl-5-(4-phenylbenzoyl)-3,4-dihydro-1H-pyrido[4,3-b]indole-8-sulfonic acid

Curated SMILES: C1CN(CC2=C1N(C3=C2C=C(C=C3)S(=O)(=O)O)C(=O)C4=CC=C(C=C4)C5=CC=CC=C5)C(=O)C6=CC=CC=C6

Evidence for compound's anti-virulence activity:

Mycobacterium
Related VFcategory: Exoenzyme
Target: PtpB
Drug effect: Inhibits protein tyrosine phosphatase B (PtpB) to interfere with signal transduction pathways in macrophages.
Max phase: Preclinical (in vitro)
Publication:
Nören-Müller A, et al., 2006. Discovery of protein phosphatase inhibitor classes by biology-oriented synthesis. Proc Natl Acad Sci U S A 103(28):10606-11.