Drug details:
Molecular formula: C₂₉H₂₃BrClN₃O₃S

Standard name: (4S,6S,12bR)-4-(4-bromophenyl)-2-chloro-12-(2-methylsulfanylpyridine-3-carbonyl)-4,6,7,12b-tetrahydro-3H-indolo[2,3-a]quinolizine-6-carboxylic acid

Curated SMILES: [H][C@]12C=C(Cl)C[C@@H](C3=CC=C(Br)C=C3)N1C(C(=O)O)CC1=C2N(C(=O)C2=CC=CN=C2SC)C2=C1C=CC=C2

Evidence for compound's anti-virulence activity:

Mycobacterium
Related VFcategory: Exoenzyme
Target: PtpB
Drug effect: Inhibits protein tyrosine phosphatase B (PtpB) to interfere with signal transduction pathways in macrophages.
Max phase: Preclinical (in vitro)
Publication:
Nören-Müller A, et al., 2006. Discovery of protein phosphatase inhibitor classes by biology-oriented synthesis. Proc Natl Acad Sci U S A 103(28):10606-11.