Drug details:
Molecular formula: C₂₁H₁₆N₂O₉

Standard name: 5-[3-[(E)-3-(3-hydroxy-2-methoxycarbonyl-4-nitrophenoxy)prop-1-enyl]phenyl]-1,2-oxazole-3-carboxylic acid

Curated SMILES: COC(=O)C1=C(C=CC(=C1O)[N+](=O)[O-])OC/C=C/C2=CC(=CC=C2)C3=CC(=NO3)C(=O)O

Evidence for compound's anti-virulence activity:

Mycobacterium
Related VFcategory: Exoenzyme
Target: PtpB
Drug effect: Inhibits protein tyrosine phosphatase B (PtpB) to interfere with signal transduction pathways in macrophages.
Max phase: Preclinical (in vitro)
Publication:
Beresford NJ, et al., 2009. Inhibition of MptpB phosphatase from Mycobacterium tuberculosis impairs mycobacterial survival in macrophages. J Antimicrob Chemother 63(5):928-36.