Drug details:
Molecular formula: C₂₁H₂₀N₂O₃S

Standard name: N-(4-butylphenyl)-2-oxo-1H-benzo[cd]indole-6-sulfonamide

Synonyms:

N-(4-butylphenyl)-2-oxo-1H-benzo[cd]indole-6-sulfonamide N-(4-butylphenyl)-3-oxo-2-azatricyclo[6.3.1.0^{4,12}]dodeca-1(11),4,6,8(12),9-pentaene-9-sulfonamide

Curated SMILES: CCCCC1=CC=C(C=C1)NS(=O)(=O)C2=C3C=CC=C4C3=C(C=C2)NC4=O

Evidence for compound's anti-virulence activity:

Mycobacterium
Related VFcategory: Exoenzyme
Target: PtpB
Drug effect: Inhibits protein tyrosine phosphatase B (PtpB) to interfere with signal transduction pathways in macrophages.
Max phase: Preclinical (in vitro)
Publication:
Chen L, et al., 2010. Identification and characterization of novel inhibitors of mPTPB, an essential virulent phosphatase from Mycobacterium tuberculosis. ACS Med Chem Lett 1(7):355-359.