Drug details:
Molecular formula: C₁₅H₁₆N₂O₃

Standard name: 5-acetamido-2-(2,5-dimethylpyrrol-1-yl)benzoic acid

Synonyms:

5-Acetamido-2-(2,5-dimethyl-1H-pyrrol-1-yl)benzoic acid 5-acetamido-2-(2,5-dimethylpyrrol-1-yl)benzoic acid 2-(2,5-DIMETHYLPYRROL-1-YL)-5-ACETAMIDOBENZOIC ACID 5-Acetamido-2-(2,5-dimethyl-1H-pyrrol-1-yl)benzoicacid 5-(Acetylamino)-2-(2,5-dimethyl-1h-pyrrol-1-yl)benzoicacid 2-(2,5-DIMETHYL-1H-PYRROL-1-YL)-5-ACETAMIDOBENZOIC ACID Benzoic acid, 5-(acetylamino)-2-(2,5-dimethyl-1H-pyrrol-1-yl)-

Curated SMILES: CC1=CC=C(N1C2=C(C=C(C=C2)NC(=O)C)C(=O)O)C

Evidence for compound's anti-virulence activity:

Mycobacterium
Related VFcategory: Exoenzyme
Target: PtpA
Drug effect: Inhibits protein tyrosine phosphatase PtpA to disrupt phagosome acidification and maturation.
Max phase: Preclinical (in vitro)
Publication:
Manger M, et al., 2005. Discovery of Mycobacterium tuberculosis protein tyrosine phosphatase A (MptpA) inhibitors based on natural products and a fragment-based approach. Chembiochem 6(10):1749-53.