Drug details:
Molecular formula: C₂₃H₂₀BrFN₂O₃

Standard name: methyl (1S,12S)-16-[(3-bromo-4-fluorophenyl)methyl]-13-oxo-3,16-diazatetracyclo[10.3.1.02,10.04,9]hexadeca-2(10),4,6,8-tetraene-14-carboxylate

Curated SMILES: COC(=O)C1C[C@H]2C3=C(C[C@@H](C1=O)N2CC4=CC(=C(C=C4)F)Br)C5=CC=CC=C5N3

Evidence for compound's anti-virulence activity:

Mycobacterium
Related VFcategory: Exoenzyme
Target: PtpB
Drug effect: Inhibits protein tyrosine phosphatase B (PtpB) to interfere with signal transduction pathways in macrophages.
Max phase: Preclinical (in vitro)
Publication:
Nören-Müller A, et al., 2008. Discovery of a new class of inhibitors of Mycobacterium tuberculosis protein tyrosine phosphatase B by biology-oriented synthesis. Angew Chem Int Ed Engl 47(32):5973-7.