Drug details:
Molecular formula: C₃₂H₃₈FN₅O₆S

Standard name: 5-[2-cyclohexyl-4-[[1-[6-[(4-fluoro-2-methylphenyl)sulfonylamino]hexyl]triazol-4-yl]methoxy]phenyl]-1,2-oxazole-3-carboxylic acid

Synonym:

5-[2-Cyclohexyl-4-[[1-[6-[[(2-methyl-4-fluorophenyl)sulfonyl]amino]hexyl]-1H-1,2,3-triazole-4-yl]methoxy]phenyl]isoxazole-3-carboxylic acid

Curated SMILES: CC1=C(C=CC(=C1)F)S(=O)(=O)NCCCCCCN2C=C(N=N2)COC3=CC(=C(C=C3)C4=CC(=NO4)C(=O)O)C5CCCCC5

Evidence for compound's anti-virulence activity:

Mycobacterium
Related VFcategory: Exoenzyme
Target: PtpB
Drug effect: Inhibits protein tyrosine phosphatase B (PtpB) to interfere with signal transduction pathways in macrophages.
Max phase: Preclinical (in vitro)
Publication:
Tan LP, et al., 2009. High-throughput discovery of Mycobacterium tuberculosis protein tyrosine phosphatase B (MptpB) inhibitors using click chemistry. Org Lett 11(22):5102-5.