Drug details:
Molecular formula: C₁₂H₉BrN₄

Standard name: 4-(5-bromo-1H-indol-3-yl)pyrimidin-2-amine

Synonyms:

Meridianin C 2-Pyrimidinamine, 4-(5-bromo-1H-indol-3-yl)-

Curated SMILES: NC1=NC(C2=CNC3=CC=C(Br)C=C32)=CC=N1

Evidence for compound's anti-virulence activity:

Staphylococcus
Related VFcategory: Biofilm
Target: Not determined
Drug effect: Inhibits biofilm formation and increases the potency of colistin.
Max phase: Preclinical (in vitro)
Publication:
Huggins WM, et al., 2018. Meridianin D Analogues Display Antibiofilm Activity against MRSA and Increase Colistin Efficacy in Gram-Negative Bacteria. ACS Med Chem Lett 9(7):702-707.