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3-hydroxy-2-phenyldiazenylbut-2-enoic acid

Drug details:
Molecular formula: C10H10N2O3

Classification: Phenylhydrazines; Benzene and substituted derivatives; Benzenoids; Organic compounds;
Chemical structure:
Depiction based on curated SMILES CH 3 O N HN O OH

Evidence for compound's anti-virulence activity:

Staphylococcus
Related VFcategory: Others; Adherence; Biofilm
Target: SrtA
Drug effect: Inhibits SrtA-mediated adesion and biofilm formation.
Max phase: Preclinical (in vitro)
Publication:
Maggio B, et al., 2016. Discovery of a New Class of Sortase A Transpeptidase Inhibitors to Tackle Gram-Positive Pathogens: 2-(2-Phenylhydrazinylidene)alkanoic Acids and Related Derivatives. Molecules 21(2):241.








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