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Compound category: Benzene and substituted derivatives
(total 28 related compounds in database, current show from 1 to 10)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
ML364 Depiction based on curated SMILES S F F F S O O HN H 3 C O N H N Klebsiella
Pseudomonas
Staphylococcus		 Biofilm; Biofilm
Pyocyanin
Biofilm		 Preclinical (in vivo)
Preclinical (in vivo)
Preclinical (in vivo)		 Zhang Y, et al. 2022. Front Microbiol
2-hydroxy-5-[2-[4-(2-phenyl-1,3-thiazol-4-yl)phenyl]-1,3-thiazol-4-yl]benzamide Depiction based on curated SMILES S OH N N NH 2 S O Enterococcus
Staphylococcus		 Others; Adherence; Biofilm
Others; Adherence; Biofilm		 Preclinical (in vitro)
Preclinical (in vitro)		 Oniga SD, et al. 2017. Molecules
2-morpholin-4-yl-5-(3-thiophen-2-ylprop-2-ynoylamino)benzoic acid Depiction based on curated SMILES N H OH O S O N O Staphylococcus Others Preclinical (in vitro) Chenna BC, et al. 2010. Eur J Med Chem
2-morpholin-4-yl-5-[[(2e)-3-(2-thienyl)prop-2-enoyl]amino]benzamide Depiction based on curated SMILES N H NH 2 O S O N O Staphylococcus Others Preclinical (in vitro) Chenna BC, et al. 2010. Eur J Med Chem
2-morpholin-4-yl-5-[[(E)-3-thiophen-2-ylprop-2-enoyl]amino]benzoic acid Depiction based on curated SMILES N H OH O S O N O Staphylococcus Others Preclinical (in vitro) Chenna BC, et al. 2010. Eur J Med Chem
2-morpholin-4-yl-5-[[(Z)-3-thiophen-2-ylprop-2-enoyl]amino]benzoic acid Depiction based on curated SMILES HN OH O S O N O Staphylococcus Others Preclinical (in vitro) Chenna BC, et al. 2010. Eur J Med Chem
2-piperidin-1-yl-5-[[(E)-3-thiophen-2-ylprop-2-enoyl]amino]benzoic acid Depiction based on curated SMILES N H OH O S O N Staphylococcus Others Preclinical (in vitro) Chenna BC, et al. 2010. Eur J Med Chem
3-hydroxy-2-phenyldiazenylbut-2-enoic acid Depiction based on curated SMILES CH 3 O N HN O OH Staphylococcus Others; Adherence; Biofilm Preclinical (in vitro) Maggio B, et al. 2016. Molecules
4-(4-chlorophenyl)-2-[4-(2-phenyl-1,3-thiazol-4-yl)phenyl]-1,3-thiazole Depiction based on curated SMILES N N S Cl S Enterococcus
Staphylococcus		 Others; Adherence; Biofilm
Others; Adherence; Biofilm		 Preclinical (in vitro)
Preclinical (in vitro)		 Oniga SD, et al. 2017. Molecules
4-[2-[4-(2-phenyl-1,3-thiazol-4-yl)phenyl]-1,3-thiazol-4-yl]benzonitrile Depiction based on curated SMILES N S N S N Enterococcus
Staphylococcus		 Others; Adherence; Biofilm
Others; Adherence; Biofilm		 Preclinical (in vitro)
Preclinical (in vitro)		 Oniga SD, et al. 2017. Molecules
   


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