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Compound category:
Benzenoids
(total
8
related compounds in database)
Compound name
2D structure
Target pathogen(s)
Related VF/VFcategory
Max phase
Reference(s)
(4Z)-2-benzyl-4-[(3-bromo-4-methoxyphenyl)methylidene]-5-(trifluoromethyl)pyrazol-3-one
Depiction based on curated SMILES
Br
F
F
F
O
H
3
C
N
N
O
Haemophilus
LOS
Preclinical (
in vitro
)
Xu Y, et al. 2018.
Bioorg Med Chem
1-Phenyl-3-(trifluoromethyl)-4-[(Z)-3-(benzyloxy)benzylidene]-2-pyrazoline-5-one
Depiction based on curated SMILES
F
F
F
O
N
N
O
Haemophilus
LOS
Preclinical (
in vitro
)
Xu Y, et al. 2018.
Bioorg Med Chem
1-Phenyl-3-(trifluoromethyl)-4-[(Z)-3-bromo-4-methoxybenzylidene]-2-pyrazoline-5-one
Depiction based on curated SMILES
Br
F
F
F
O
H
3
C
N
N
O
Haemophilus
LOS
Preclinical (
in vitro
)
Xu Y, et al. 2018.
Bioorg Med Chem
(4Z)-4-[(4-chlorophenyl)methylidene]-2-phenyl-5-(trifluoromethyl)pyrazol-3-one
Depiction based on curated SMILES
F
F
F
N
Cl
O
N
Haemophilus
LOS
Preclinical (
in vitro
)
Xu Y, et al. 2018.
Bioorg Med Chem
3-[(4Z)-4-[(3-bromo-4-methoxyphenyl)methylidene]-5-oxo-3-(trifluoromethyl)pyrazol-1-yl]-N-(2-hydroxyethyl)benzamide
Depiction based on curated SMILES
Br
F
F
F
OH
NH
O
CH
3
O
N
N
O
Haemophilus
LOS
Preclinical (
in vitro
)
Xu Y, et al. 2018.
Bioorg Med Chem
3-[(4Z)-4-[(3-bromo-4-methoxyphenyl)methylidene]-5-oxo-3-(trifluoromethyl)pyrazol-1-yl]benzoic acid
Depiction based on curated SMILES
O
Br
F
F
F
HO
O
H
3
C
N
N
O
Haemophilus
LOS
Preclinical (
in vitro
)
Xu Y, et al. 2018.
Bioorg Med Chem
4-[(4Z)-4-(3-bromo-4-methoxybenzylidene)-5-oxo-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-1-yl]benzoic acid
Depiction based on curated SMILES
O
Br
F
F
F
HO
O
H
3
C
N
N
O
Haemophilus
LOS
Preclinical (
in vitro
)
Xu Y, et al. 2018.
Bioorg Med Chem
ethyl 2-[(4Z)-4-[(3-bromo-4-methoxyphenyl)methylidene]-5-oxo-1-phenylpyrazol-3-yl]acetate
Depiction based on curated SMILES
Br
H
3
C
O
H
3
C
O
N
N
O
O
Haemophilus
LOS
Preclinical (
in vitro
)
Xu Y, et al. 2018.
Bioorg Med Chem
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