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Compound category: Indoles and derivatives
(total 17 related compounds in database, current show from 11 to 17)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
4-(6-bromo-1-methylindol-3-yl)pyrimidin-2-amine Depiction based on curated SMILES NH 2 Br N CH 3 N N Staphylococcus Biofilm Preclinical (in vitro) Huggins WM, et al. 2018. ACS Med Chem Lett
4-(6-bromo-1-propylindol-3-yl)pyrimidin-2-amine Depiction based on curated SMILES Br N NH 2 H 3 C N N Staphylococcus Biofilm Preclinical (in vitro) Huggins WM, et al. 2018. ACS Med Chem Lett
Meridianin D Depiction based on curated SMILES N H N Br NH 2 N Mycobacterium
Staphylococcus		 Biofilm
Biofilm		 Preclinical (in vitro)
Preclinical (in vitro)		 Zeiler MJ, et al. 2020. ChemMedChem; Brackett SM, et al. 2020. RSC Med Chem
Huggins WM, et al. 2018. ACS Med Chem Lett
4-(6-iodo-1H-indol-3-yl)pyrimidin-2-amine Depiction based on curated SMILES N I NH 2 N H N Staphylococcus Biofilm Preclinical (in vitro) Huggins WM, et al. 2018. ACS Med Chem Lett
5-(5-bromo-1H-indol-3-yl)-1H-imidazol-2-amine Depiction based on curated SMILES NH 2 N N H Br N H Staphylococcus Biofilm Preclinical (in vitro) Huggins WM, et al. 2018. ACS Med Chem Lett
5-(6-bromo-1H-indol-3-yl)-1H-imidazol-2-amine Depiction based on curated SMILES Br N H N N H H 2 N Mycobacterium
Staphylococcus		 Biofilm
Biofilm		 Preclinical (in vitro)
Preclinical (in vitro)		 Brackett SM, et al. 2020. RSC Med Chem
Huggins WM, et al. 2018. ACS Med Chem Lett
N-benzyl-4-(5-bromo-1H-indol-3-yl)pyrimidin-2-amine Depiction based on curated SMILES Br HN N N NH Mycobacterium
Staphylococcus		 Biofilm
Biofilm		 Preclinical (in vitro)
Preclinical (in vitro)		 Huggins WM, et al. 2018. ACS Med Chem Lett; Zeiler MJ, et al. 2020. ChemMedChem; Brackett SM, et al. 2020. RSC Med Chem
   
   
   
   
   
   
   


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