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Compound category: Organoheterocyclic compounds
(total 4 related compounds in database)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
5-nitro-7-[(3-phenylpyrrolidin-1-yl)methyl]quinolin-8-ol Depiction based on curated SMILES N OH O N _ O + N Chlamydia
Yersinia		 TTSS (Type III secretion system)
TTSS (Type III secretion system)		 Preclinical (in vitro)
Preclinical (in vitro)		 Enquist PA, et al. 2012. Bioorg Med Chem Lett
5-nitro-7-[(4-phenyl-1-piperazinyl)methyl]-8-quinolinol Depiction based on curated SMILES N OH O N N _ O + N Chlamydia
Yersinia		 TTSS (Type III secretion system)
TTSS (Type III secretion system)		 Preclinical (in vitro)
Preclinical (in vitro)		 Enquist PA, et al. 2012. Bioorg Med Chem Lett
7-[[4-(4-fluorophenyl)piperazin-1-yl]methyl]-5-nitroquinolin-8-ol Depiction based on curated SMILES N OH F O N N _ O + N Chlamydia
Yersinia		 TTSS (Type III secretion system)
TTSS (Type III secretion system)		 Preclinical (in vitro)
Preclinical (in vitro)		 Enquist PA, et al. 2012. Bioorg Med Chem Lett
(E)-N'-(3,5-Dibromo-2-hydroxybenzylidene)nicotinohydrazide Depiction based on curated SMILES N OH Br O Br N N H Chlamydia
Escherichia
Salmonella		 TTSS (Type III secretion system)
TTSS (Type III secretion system)
TTSS (SPI-1 encode); TTSS (SPI-2 encode)		 Preclinical (in vitro)
Preclinical (in vitro)
Preclinical (in vitro)		 Bailey L, et al. 2007. FEBS Lett
Tree JJ, et al. 2009. Infect Immun; Wang D, et al. 2011. J Biol Chem
Negrea A, et al. 2007. Antimicrob Agents Chemother
   
   
   
   
   
   
   
   
   
   
   
   
   


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