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Compound category: Piperazines
(total 17 related compounds in database, current show from 11 to 17)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
4-{4-[(2E)-3-phenylprop-2-en-1-yl]piperazin-1-yl}-5H-pyrimido[5,4-b]indole Depiction based on curated SMILES N HN N N N Salmonella Biofilm Preclinical (in vitro) Robijns SC, et al. 2012. FEMS Immunol Med Microbiol
7,8-dimethoxy-4-{4-[(2E)-3-phenylprop-2-en-1-yl]piperazin-1-yl}-5H-pyrimido[5,4-b]indole Depiction based on curated SMILES N H N H 3 C N N N CH 3 O O Salmonella Biofilm Preclinical (in vitro) Robijns SC, et al. 2012. FEMS Immunol Med Microbiol
7-methoxy-4-{4-[(2E)-3-phenylprop-2-en-1-yl]piperazin-1-yl}-5H-pyrimido[5,4-b]indole Depiction based on curated SMILES N N CH 3 N N HN O Salmonella Biofilm Preclinical (in vitro) Robijns SC, et al. 2012. FEMS Immunol Med Microbiol
7-methyl-4-{4-[(2E)-3-phenylprop-2-en-1-yl]piperazin-1-yl}-5H-pyrimido[5,4-b]indole Depiction based on curated SMILES N N CH 3 N N NH Salmonella Biofilm Preclinical (in vitro) Robijns SC, et al. 2012. FEMS Immunol Med Microbiol
8-fluoro-4-{4-[(2E)-3-phenylprop-2-en-1-yl]piperazin-1-yl}-5H-pyrimido[5,4-b]indole Depiction based on curated SMILES N N F N N N H Salmonella Biofilm Preclinical (in vitro) Robijns SC, et al. 2012. FEMS Immunol Med Microbiol
9-methoxy-4-{4-[(2E)-3-phenylprop-2-en-1-yl]piperazin-1-yl}-5H-pyrimido[5,4-b]indole Depiction based on curated SMILES HN N CH 3 N N N O Salmonella Biofilm Preclinical (in vitro) Robijns SC, et al. 2012. FEMS Immunol Med Microbiol
N-methyl-3-(1-(4-(piperazin-1-yl)phenyl)-5-(4'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl)-1H-pyrazol-3-yl)propanamide Depiction based on curated SMILES F F F N H O N N CH 3 N N H Acinetobacter
Salmonella
Biofilm
Biofilm
Preclinical (in vitro)
Preclinical (in vitro)
Moshiri J, et al. 2018. Front Microbiol
   
   
   
   
   
   
   


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