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Compound category: Quinolines and derivatives
(total 6 related compounds in database)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
(2R,3S,4S,5S,6R)-2-[(R)-hydroxy-(4-isoquinolin-5-yl-2-methylphenyl)methyl]-6-(hydroxymethyl)oxane-3,4,5-triol Depiction based on curated SMILES HO OH OH OH O HO H CH 3 N Escherichia Type 1 fimbriae Preclinical (in vivo) Mydock-McGrane L, et al. 2016. J Med Chem
(2R,3S,4S,5S,6R)-2-[(R)-[4-(1-aminoisoquinolin-7-yl)-2-methylphenyl]-hydroxymethyl]-6-(hydroxymethyl)oxane-3,4,5-triol Depiction based on curated SMILES HO OH OH OH O HO H CH 3 NH 2 N Escherichia Type 1 fimbriae Preclinical (in vivo) Mydock-McGrane L, et al. 2016. J Med Chem
7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isoquinolin-1-amine Depiction based on curated SMILES NH 2 N B CH 3 CH 3 CH 3 H 3 C O O Escherichia Type 1 fimbriae Preclinical (in vivo) Mydock-McGrane L, et al. 2016. J Med Chem
7-[4-[(R)-hydroxy-[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]methyl]-3-methylphenyl]-2H-isoquinolin-1-one Depiction based on curated SMILES HO OH OH OH O HO H CH 3 O N H Escherichia Type 1 fimbriae Preclinical (in vivo) Mydock-McGrane L, et al. 2016. J Med Chem
7-[4-[(R)-hydroxy-[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]methyl]-3-methylphenyl]-3,4-dihydro-2H-isoquinolin-1-one Depiction based on curated SMILES HO OH OH OH O HO H CH 3 O N H Escherichia Type 1 fimbriae Preclinical (in vivo) Mydock-McGrane L, et al. 2016. J Med Chem
2-[4-[3-(furan-2-yl)-5-phenyl-1,2-oxazol-4-yl]phenyl]quinoline-4-carboxylic acid Depiction based on curated SMILES O N O N HO O Escherichia
Salmonella
TTSS (Type III secretion system)
TTSS (SPI-2 encode)
Preclinical (in vitro)
Preclinical (in vitro)
El Qaidi S, et al. 2018. Front Cell Infect Microbiol
   
   
   
   
   
   
   
   
   


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