Drug details:
Molecular formula: C₁₄H₉Br₂N₃O₄

Standard name: N-[(E)-(3,5-dibromo-2-hydroxyphenyl)methylideneamino]-4-nitrobenzamide

Synonyms:

N'-[(E)-(3,5-Dibromo-2-hydroxyphenyl)methylidene]-4-nitrobenzohydrazide N'-[(E)-(3,5-Dibromo-2-hydroxyphenyl)methylidene]-4-nitrobenzohydrazide # N-[(E)-(3,5-dibromo-2-hydroxy-phenyl)methyleneamino]-4-nitro-benzamide

Curated SMILES: O=C(N/N=C/C1=CC(Br)=CC(Br)=C1O)C1=CC=C([N+](=O)[O-])C=C1

Evidence for compound's anti-virulence activity:

Salmonella
Related VF: TTSS (SPI-1 encode); TTSS (SPI-2 encode)
Target: Not determined
Drug effect: Efficiently affected SPI1 and SPI2 activity.
Max phase: Preclinical (in vitro)
Publication:
Negrea A, et al., 2007. Salicylidene acylhydrazides that affect type III protein secretion in Salmonella enterica serovar typhimurium. Antimicrob Agents Chemother 51(8):2867-76.

Yersinia
Related VF: TTSS (Type III secretion system)
Target: Not determined
Drug effect: Blocks translocation of Yop effectors.
Max phase: Preclinical (in vitro)
Publications:
Kauppi AM, et al., 2003. Targeting bacterial virulence: inhibitors of type III secretion in Yersinia. Chem Biol 10(3):241-9.
Nordfelth R, et al., 2005. Small-molecule inhibitors specifically targeting type III secretion. Infect Immun 73(5):3104-14.